Exploration of Bioactive Compounds, Antibacterial and Antibiofilm Activity of Marine Macroalgae (Ulva rigida) Isolated from Rameshwaram Coastal Region

Antibacterial resistance is a critical issue that has led to an increase in demand for new antibacterial compounds. In this point of view, present study was evaluating the antimicrobial and antibiofilm activity of algae extract against food isolates. Totally 7 types of bacterial genera were observed from meat samples and subjected to screening the biofilm producing isolates. Among the 18 isolates, 77.7% of were biofilm producers, which were confirmed with Congo red agar plate method. Among the 7 test pathogens, K. pneumoniae and E. faecalis were highly suppressed, 10mg of concentration was suppressed the all isolates. In case of antibiofilm process, highest activity was observed against above-mentioned isolates. The GC-MS result showed the presence of several important antimicrobial fatty acids like 9, 12-Octadecadienoic acid, Hexadecanedioic acid, 1,15-Pentadecanedioic acid. In this study, Ulva rigida was shown to have a wide spectrum of antimicrobial activity and be antibiofilm activity at low concentration; therefore, Ulva rigida extract could have important application in the field of antimicrobial production as alternative to antibiotics.

M. Manivannan1, G Subramanian2 and D. Jegadeeshkumar*3 Click here to download file

Research Article | Published online : 29-May-2023