Research Journal of Agricultural Sciences Vol : 6 - Issue : 4 ; 716-719 K A Gaikwad, R A Durgude* and P B Parkhe* Depertment of Horticulture, Dr. Panjabrao Deshmukh Krishi Vidyapeeth, Akola - 444 104, Maharashtra, India *Mahatma Phule Krishi Vidyapeeth, Rahuri, District Ahmednagar - 413 722, Maharashtra, India Abstract Plant disease is one of the major biotic stresses affecting crop yield substantially. Due to development of new varieties and agricultural practices minor diseases in the past become important these days. Though genetic makeup controls interaction between pathogen and host, the environment affects it to a great extent. Use of a single method is not enough to control disease effectively. As all methods have their own drawbacks, combining two or more method minimizes the drawbacks. Combination of chemical and genetic control method proved to be more effective and long lasting in controlling many plant diseases.